DIABETIC KETOACIDOSIS (DKA)

What do you want to read today?

• Definition

• Pathophysiology

• Clinical Manifestations

• Complications

• Management

Definition

Diabetic ketoacidosis is an acute complication of diabetes mellitus type 1. It occurs when insulin is insufficient to control the hyperglycemia and the ketone body production. Because it may be associated with severe dehydration and acidosis, it is a MEDICAL EMERGENCY and a frequent reason for admission to an Intensive Care Unit.

Pathophysiology

Clinical Manifestations

• nausea, vomiting, abdominal pain

• dehydration, polyuria, hypotension, shock

• hyperglycemia (not necessarily always present)

• ketosis

• acidosis

• fruity breath odor

• electrolyte imbalances (e.g. hyponatremia, hyperkalemia)

Complications

Management

DKA Links:

Back to Diabetes Mellitus

Back to Critical Care Medicine Website

Acute Emergencies of DM: Diabetic Ketoacidosis

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